Invokana is part of a class of drugs called SGLT2 inhibitors, which includes other drugs such as Farxiga and Glyxambi that are used to help regulate blood sugar levels in adult patients with Type 2 diabetes. This class of drugs, however, is not approved to treat Type 1 diabetes patients. Along with other members of the SGLT2 inhibitor class, Invokana works by triggering the kidneys to take sugar from the body through the urine to lower blood sugar levels.
Invokana, which contains the active ingredient canagliflozin, is in a class of drugs called sodium-glucose cotransporter-2 (SGLT2) inhibitors. Other SGLT2 inhibitors are marketed under various brand names and are manufactured by drug makers Janssen, AstraZeneca and Boehringer Ingelheim.
What are the Risks of Invokana?
The United States Food and Drug Administration (FDA) issued a safety communication regarding SGLT2 inhibitors, including Invokana, on the basis that the drugs may lead to ketoacidosis, a serious condition where the body produces high levels of blood acids called ketones that may require hospitalization.
Invokana risks may include the following injuries or complications:
- Ketoacidosis, which may lead to diabetic coma or death
- Cardiovascular complications
- Kidney damage or failure
- Bone fracture risk
- Decreased bone mineral density
Invokana Side Effects
Invokana, like many drugs, can come with a number of side effects, ranging from common to rare, which can include:
- Low blood sugar
- Frequent urination
- Urinary tract infection
- Low blood pressure
- Faintness or weakness
- High levels of magnesium in the blood
- High levels of potassium in the blood
- Allergic reaction
- Dry mouth
- High levels of cholesterol
- High levels of hemoglobin
- Kidney disease
- Stomach cramps
Invokana and Ketoacidosis
(In clinical trials) Patients on Invokana were significantly more likely to develop ketoacidosis than patients on other SGLT2 inhibitors. Ketoacidosis normally involves very high blood-sugar levels. However, many Invokana patients with normal or mildly-elevated blood-sugar have developed ketocidosis. The unusual symptoms can delay diagnosis and treatment until it becomes life-threatening.
Signs and symptoms of DKA can include:
- Excessive thirst
- Frequent urination
- Nausea and vomiting
- Abdominal pain
- Weakness or fatigue
- Shortness of breath
- Fruity-scented breath
DKA can be triggered by factors such as heart attack, emotional or physical trauma, surgery, high fever, stress, or alcohol or drug abuse.
Call the Houssiere Durant Houssiere, LLP law firm or fill our contact form to see if you are eligible for a potential Invokana lawsuit. Call us at 1-888-881-8100 or 713-626-3700 for a free consultation.
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